See where our research is happening and read about the studies and research teams.

You may have to zoom in to see multiple projects in areas where they are highly concentrated, for example in London. Use the + and - symbols on the map to aid your search.

1. Building resilience to Ulcerative Colitis

Understanding stress and building resilience in new-onset Ulcerative Colitis.Read more

2. Vascular invasion in colorectal cancers

The characterisation of early metastatic phenotype in colorectal cancer with a focus on identification of morphological and molecular determinants of vascular invasion.Read more

3. Predicting patient response to rectal cancer treatment

This study focuses on tailoring rectal cancer treatment with an artificial intelligence that learns from multiple hospitals’ data without data ever leaving those hospitalsRead more

4. Metastatic bowel cancer treatment

Bowel & Cancer Research is funding a PhD which aims to identify molecular determinants of response to oxaliplatin in metastatic bowel cancer, improving outcomes and limiting toxicity.Read more

5. The role of exosomes in the spread of bowel cancer

Investigating the tiny packages released by bowel cancer cells called vesicles which can leave the bowel and spread. In this way, bowel cancer creates suitable environments for a metastasis to establish.Read more

6. A new approach to gastroparesis and nausea

Understanding the mechanisms behind the movement within the stomach could pave a way to new treatments for nausea.Read more

7. Sonic therapy and nanotechnology to treat bowel cancer

Can a combination of novel approaches open up new avenues for the treatment of bowel cancer?Read more

8. Developing neurons: their potential for tissue repair

Examining the differences between newly formed and adult neurons can aid our understanding of their potential in tissue repair.Read more

9. Experiences of Inflammatory Bowel Disease among BME patients

Rates of IBD within the BME community are increasing but little is known about the experiences of those who live with the condition.Read more

10. Harnessing MRI for the diagnosis of chronic intestinal pseudo obstruction

A new way of detecting patients with possible chronic intestinal pseudo obstruction in needed.Read more

11. Unravelling tumour-immune interactions in bowel cancer

Developing an improved understanding of the variability of patient response to new checkpoint inhibitor class drugs.Read more

12. Patient experience of recurrent rectal cancer

To improve treatment, we need a better understanding of the effect on patients' quality of life when rectal cancer reoccurs.Read more

13. Modelling genetic differences in bowel cancer tumours

The many genetic differences in bowel cancer tumours from patient to patient make them difficult to treat. Can we deliver a genetic tool to better study these and advance treatment?Read more

14. Mutation in the BRAF gene in colorectal cancer

How does the BRAF gene mutation drive the development of colorectal cancer and how can we improve outcomes for these patients?Read more

15. The role of specific T cells in Inflammatory Bowel Disease

The first in depth analysis of resident memory T cells (Trm) and their role in Inflammatory Bowel Disease.Read more

16. Ostique's stylish stoma bags

This study is looking to design a range of revolutionary new stoma products.Read more

17. Decoy bypass

Using nutrients to mimic the effect of bariatric surgery to tackle obesity and type II diabetes.Read more

18. CIPO children and the 100k Genomes Project

Funded by our partner the Pseudo Obstruction Research Trust, this project aims to gather vital genetic data for research.Read more

19. Improving outcomes after bowel surgery

Can we maintain the health of bowel that is resting after surgery by feeding it?Read more

20. Constipation in IBS

This study will examine the effect of an IBS therapy to understand its mechanism to treat pain without side effects of constipation.Read more

21. Immune responses in Crohn's disease

This study is looking for the key genes involved in driving the response of the immune system in Crohn's disease.Read more

22. Tissue engineering for Ulcerative Colitis

Can healthy tissue be engineered to replace that damaged by Ulcerative Colitis?Read more

23. Nutrient sensing and obesity

Our new PhD seeks to understand how nutrient sensing changes at a molecular level in obese humans.Read more

24. Relationship between IBS and EDS

Our new PhD aims to establish the relationship between IBS and EDS in order to improve care.Read more

25. Understanding responses to therapy in rectal cancer

Our new PhD aims to develop our understanding of why individual patients respond differently to treatment for rectal cancer.Read more

26. Cell therapies for Hirschprung's

Our new PhD aims to improve treatments for babies born with Hirschprung's, a rare but life threatening bowel condition.Read more

27. Early detection of anastomosis leak

When bowel is rejoined after surgery, in 1 in 10 cases it doesn't heal properly and a leak happens in the body.Read more

28. Tackling obesity and type II diabetes

Obesity is a growing public health problem in developed countries. Can we find ways to suppress appetite without need for surgery?Read more

29. Stem cell transplantation in Crohn's disease

Stem cell transplantation has been shown to provide benefits for patients but can have serious side effects. Can we predict who will do well?Read more

30. Treating pain in Ulcerative Colitis

Our PhD student Michael Tranter is using insights from our Crohn's pain project to investigate better treatment for pain in Ulcerative ColitisRead more

31. Treating pain in Crohn's disease

This study is pinpointing the pain sensing nerves in the bowel to find better pain relief treatments for Crohn's patients.Read more

32. IBS School

Our PhD student, Valentina Passananti, is supporting people with IBS to find effective ways to self manage their condition.Read more

33. Diagnosing bile acid malabsorption

Often individuals with a condition called Bile Acid Malabsorption are mistakenly diagnosed with IBS or Inflammatory Bowel Disease.Read more

34. What is normal bowel function?

We need healthy volunteers for this study which will define the range for normal bowel function.Read more

35. A role for aspirin after bowel cancer surgery

Our PhD student, Danny Legge, is investigating a possible role for aspirin to improve how patients respond to the treatment they receive after surgery.Read more

36. Targeting areas of low oxygen in bowel tumours

Our PhD student, Hannah Bolland, is examining areas of tumours that are low in oxygen because these are hard to treat and so more dangerous.Read more

37. Contrast Enhanced Ultrasound for rectal cancer staging

Scanning for rectal cancer using CT and MRI cannot identify spread in areas such as lymph nodes and blood vessels, can we develop this?Read more

38. Harnessing cell competition to treat bowel cancer

Can we help normal cells to win the cell competition with cancer cells? At each stage of development cancer cells compete with their neighbours for survival.Read more

39. Targeting APC loss to treat bowel cancer

Our PhD student, Hannah Shailes, aims to pinpoint new therapies by researching a mutation in the gene Adenomatis Polyposis Coli (APC).Read more

40. Understanding survival in advanced bowel cancer

Some people with advanced bowel cancer respond very well to treatment. Can this group hold clues to a better prognosis for everyone?Read more

41. Studying the microbiome to target bowel cancer

The “microbiome” refers to the trillions of bacteria that live in our colon. Recent studies have shown that this is altered in bowel cancer.Read more

42. Exercising with a stoma

No other study has evaluated the benefits of a physical activity intervention specifically for patients with a stoma.Read more

43. The role of COMMD1 in bowel cancer

COMMD1 is a molecule that is found in our cells. Researchers believe that it may be very important in how bowel cancer develops.Read more