What is a clinical trial?
Clinical trials help researchers (and society in general) to determine whether a particular treatment or intervention is safe, effective and acceptable to patients. Clinical trials cover many aspects of how we treat diseases including drug (pharmacological) therapies (either new drugs or existing ones used in a different way); medical devices; surgical innovations and even behavioural studies and those involving the completion of questionnaires.
A trial is a scientific way of undertaking a study that aims to answer one or more specific questions. Clinical trials bring research which started often in a laboratory into clinical practice within the NHS and beyond. It can take many years for basic laboratory science to make it into clinical practice because the safeguards presented at each stage of the process ensure that the end product is safe and effective in humans.
Treatments such as chemotherapy and radiotherapy for bowel cancer, anti-TNF for IBD patients and advances such as laparascopic (keyhole) surgery have all come about through a process starting with an idea (hypothesis), following a process of discovery and testing and ending with a clinical trial in a human population.
Our PhD student, Valentina Passananti, is supporting people with IBS to find effective ways to self manage their condition.Read more
This trial aims to establish how Sacral Neuromodulation (SNM) works and how well it works. Patients who meet the current national criteria for SNM will be invited to participate in the trial.Read more
We need healthy volunteers for this study which will define the range for normal bowel function.Read more
This study is looking to use technology to bring the power of MRI into the management of chronic conditions such as Crohn's disease.Read more
No other study has evaluated the benefits of a physical activity intervention specifically for patients with a stoma.Read more
A National Institute for Health Research funded trial to develop an evidence-based pathway for the treatment of chronic constipation in the NHS.Read more