A new approach to gastroparesis and nausea

Understanding the mechanisms behind the movement within the stomach could pave a way to new treatments for nausea. Read more

Developing neurons: their potential for tissue repair

Examining the differences between newly formed and adult neurons can aid our understanding of their potential in tissue repair. Read more

Experiences of Inflammatory Bowel Disease among BME patients

Rates of IBD within the BME community are increasing but little is known about the experiences of those who live with the condition. Read more

Harnessing MRI for the diagnosis of chronic intestinal pseudo obstruction

A new way of detecting patients with possible chronic intestinal pseudo obstruction in needed. Read more

The role of specific T cells in Inflammatory Bowel Disease

The first in depth analysis of resident memory T cells (Trm) and their role in Inflammatory Bowel Disease. Read more

CIPO children and the 100k Genomes Project

Funded by our partner the Pseudo Obstruction Research Trust, this project aims to gather vital genetic data for research. Read more

Constipation in IBS

This study will examine the effect of an IBS therapy to understand its mechanism to treat pain without side effects of constipation. Read more

Immune responses in Crohn's disease

This study is looking for the key genes involved in driving the response of the immune system in Crohn's disease. Read more

Tissue engineering for Ulcerative Colitis

Can healthy tissue be engineered to replace that damaged by Ulcerative Colitis? Read more

Nutrient sensing and obesity

Our new PhD seeks to understand how nutrient sensing changes at a molecular level in obese humans. Read more

Relationship between IBS and EDS

Our new PhD aims to establish the relationship between IBS and EDS in order to improve care. Read more

Cell therapies for Hirschprung's

Our new PhD aims to improve treatments for babies born with Hirschprung's, a rare but life threatening bowel condition. Read more

Early detection of anastomosis leak

When bowel is rejoined after surgery, in 1 in 10 cases it doesn't heal properly and a leak happens in the body. Read more

Tackling obesity and type II diabetes

Obesity is a growing public health problem in developed countries. Can we find ways to suppress appetite without need for surgery? Read more

Stem cell transplantation in Crohn's disease

Stem cell transplantation has been shown to provide benefits for patients but can have serious side effects. Can we predict who will do well? Read more

Treating pain in Ulcerative Colitis

Our PhD student Michael Tranter is using insights from our Crohn's pain project to investigate better treatment for pain in Ulcerative Colitis Read more

Treating pain in Crohn's disease

This study is pinpointing the pain sensing nerves in the bowel to find better pain relief treatments for Crohn's patients. Read more

IBS School

Our PhD student, Valentina Passananti, is supporting people with IBS to find effective ways to self manage their condition. Read more

Diagnosing bile acid malabsorption

Often individuals with a condition called Bile Acid Malabsorption are mistakenly diagnosed with IBS or Inflammatory Bowel Disease. Read more

What is normal bowel function?

We need healthy volunteers for this study which will define the range for normal bowel function. Read more

The role of Tenascin X in gut function

The project’s aim is to understand how abnormalities of Tenascin X (TNX) lead to gastrointestinal dysfunction and symptoms. Read more

MC4 receptor signalling after gastric bypass surgery

Gastric bypass surgery reduces the capacity of the stomach and shunts nutrients to the distal intestine where they are sensed by nutrient‐sensing cells (endocrine cells) present within the gut lining that release signalling hormones. This gives a feeling of satiety (being full) after the smallest meal and so patients tend to lose weight rapidly. The effect of the surgery also reverses type 2 diabetes (T2D). Read more