Sonic therapy and nanotechnology to treat bowel cancer

Can a combination of novel approaches open up new avenues for the treatment of bowel cancer? Read more

Unravelling tumour-immune interactions in bowel cancer

Developing an improved understanding of the variability of patient response to new checkpoint inhibitor class drugs. Read more

Patient experience of recurrent rectal cancer

To improve treatment, we need a better understanding of the effect on patients' quality of life when rectal cancer reoccurs. Read more

Modelling genetic differences in bowel cancer tumours

The many genetic differences in bowel cancer tumours from patient to patient make them difficult to treat. Can we deliver a genetic tool to better study these and advance treatment? Read more

New treatment for advanced bowel cancer

Advanced bowel cancer has poor survival rates. This study aims to better understand the mechanisms behind how cancer spreads around the body. Read more

Mutation in the BRAF gene in colorectal cancer

How does the BRAF gene mutation drive the development of colorectal cancer and how can we improve outcomes for these patients? Read more

Ostique's stylish stoma bags

This study is looking to design a range of revolutionary new stoma products. Read more

Improving outcomes after bowel surgery

Can we maintain the health of bowel that is resting after surgery by feeding it? Read more

Understanding responses to therapy in rectal cancer

Our new PhD aims to develop our understanding of why individual patients respond differently to treatment for rectal cancer. Read more

A role for aspirin after bowel cancer surgery

Our PhD student, Danny Legge, is investigating a possible role for aspirin to improve how patients respond to the treatment they receive after surgery. Read more

Predicting the risk of bowel cancer

Researchers investigated whether there are differences in the genes within adenomas which lead to cancer and those which do not to determine a way of predicting the risk of developing bowel cancer. Read more

Targeting areas of low oxygen in bowel tumours

Our PhD student, Hannah Bolland, is examining areas of tumours that are low in oxygen because these are hard to treat and so more dangerous. Read more

Contrast Enhanced Ultrasound for rectal cancer staging

Scanning for rectal cancer using CT and MRI cannot identify spread in areas such as lymph nodes and blood vessels, can we develop this? Read more

Harnessing cell competition to treat bowel cancer

Can we help normal cells to win the cell competition with cancer cells? At each stage of development cancer cells compete with their neighbours for survival. Read more

Targeting APC loss to treat bowel cancer

Our PhD student, Hannah Shailes, aims to pinpoint new therapies by researching a mutation in the gene Adenomatis Polyposis Coli (APC). Read more

Understanding survival in advanced bowel cancer

Some people with advanced bowel cancer respond very well to treatment. Can this group hold clues to a better prognosis for everyone? Read more

Targeting tissue stiffness to treat bowel cancer

As bowel cancer develops and progresses, there are significant changes in the organisation of the web of proteins forming the structure of bowel tissue, this helps the cancer to develop. Read more

Studying the microbiome to target bowel cancer

The “microbiome” refers to the trillions of bacteria that live in our colon. Recent studies have shown that this is altered in bowel cancer. Read more

Using monoclonal antibodies to target bowel cancer

Working towards the development of an alternative for patients with advanced bowel cancer, monoclonal antibodies (mAbs) are a type of biological therapy that work by targeting specific molecules, known as antigens, on cancer cells. Cancer cells express complex sugars on these antigens which are vital for their survival. Read more

Exercising with a stoma

No other study has evaluated the benefits of a physical activity intervention specifically for patients with a stoma. Read more

The role of COMMD1 in bowel cancer

COMMD1 is a molecule that is found in our cells. Researchers believe that it may be very important in how bowel cancer develops. Read more