Survival rates for bowel cancer vary considerably. When caught early surgery is highly effective and more than 90% of people will survive, but when caught at the very latest stage this falls to 6%.
We want a future where no one dies of bowel cancer so we fund the best science across the UK. Our researchers explore improving diagnosis and treatment as well as better understanding vital biological processes so that we can use them to find new therapies.
The PhD students that we fund are supported to pursue new ideas and will become our future experts.
Here you can learn about the research that we are funding across the UK and the work being pioneered by our PhD students.
The many genetic differences in bowel cancer tumours from patient to patient make them difficult to treat. Can we deliver a genetic tool to better study these and advance treatment?Read more
Advanced bowel cancer has poor survival rates. This study aims to better understand the mechanisms behind how cancer spreads around the body.Read more
How does the BRAF gene mutation drive the development of colorectal cancer and how can we improve outcomes for these patients?Read more
This study is looking to design a range of revolutionary new stoma products.Read more
Can we maintain the health of bowel that is resting after surgery by feeding it?Read more
Our new PhD aims to develop our understanding of why individual patients respond differently to treatment for rectal cancer.Read more
Our PhD student, Danny Legge, is investigating a possible role for aspirin to improve how patients respond to the treatment they receive after surgery.Read more
Our PhD student, Hannah Bolland, is examining areas of tumours that are low in oxygen because these are hard to treat and so more dangerous.Read more
Scanning for rectal cancer using CT and MRI cannot identify spread in areas such as lymph nodes and blood vessels, can we develop this?Read more
Can we help normal cells to win the cell competition with cancer cells? At each stage of development cancer cells compete with their neighbours for survival.Read more
Our PhD student, Hannah Shailes, aims to pinpoint new therapies by researching a mutation in the gene Adenomatis Polyposis Coli (APC).Read more
Some people with advanced bowel cancer respond very well to treatment. Can this group hold clues to a better prognosis for everyone?Read more
The “microbiome” refers to the trillions of bacteria that live in our colon. Recent studies have shown that this is altered in bowel cancer.Read more
No other study has evaluated the benefits of a physical activity intervention specifically for patients with a stoma.Read more
COMMD1 is a molecule that is found in our cells. Researchers believe that it may be very important in how bowel cancer develops.Read more